Assessing BRD

On this page, you’ll find more information about what Bovine Respiratory Disease (BRD) is and what to look for in your cattle if you suspect BRD.


Bovine Respiratory Disease (BRD) is a highly infectious and complex disease that negatively impacts the cattle industry. According to the Institute of Food and Agricultural Sciences publication, BRD is the most costly disease effecting US Cattle.1 Annual losses for producers are approaching $3 billion with their combined costs including death loss, reduced performance, treatment, and labor resources.2 And even if mortality does not occur, losses associated with disease are still significant. Healthy cattle without lung lesions return $20 more net income/hd than cattle with lung lesions.3

While BRD can refer to any disease that affects a animal’s respiratory system, BRD caused by M. haemolytica is the primary factor is severe pneumonia and death loss.4 Additionally, it’s the most frequently isolated bacteria from the pneumonic lungs and present in 75% of all diagnosed cases of BRD.4 BRD can be brought on by a number of factors, including comingling, environmental fluctuations, stress, and nutritional compromise. Spotting BRD can be tricky, but with experience, you can learn to identify BRD as soon as possible.

What are the Signs?

Recognizing the signs of BRD are critical to early intervention and disease mitigation. Listed below are the most common clinical signs to watch for. Contact your veterinarian to solicit advice for treatment and control.

4-4-003 Micotil sick calf1

Contributing Factors To BRD

In the meantime, let's take a look at factors that may have contributed to the problem. Factors like immune status, and stressors such as transport, co-mingling, and fluctuations in temperature can contribute to BRD. Taking all of this into account can help you understand how to mitigate future risks and incidence of BRD.

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About Micotil (tilmicosin injection)

Learn about an effective, flexible treatment for BRD.

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Preventing BRD

Learn about the steps you can take to actively prevent your cattle getting BRD.


Micotil® (tilmicosin injection) is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus sommi, and for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica.

Important safety information

Before using this product, it is important to read the entire product insert, including the boxed human warning.Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Not for human use. Injection of this drug in humans has been associated with fatalities. Keep out of reach of children. Do not use in automatically powered syringes. Exercise extreme caution to avoid accidental self-injection. In case of human injection, consult a physician immediately and apply ice or cold pack to injection site while avoiding direct contact with skin. Avoid contact with eyes. Always use proper drug handling procedures to avoid accidental self-injection. Consult your veterinarian on the safe handling and use of all injectable products prior to administration. For use in cattle or sheep only. Inject subcutaneously. Injection of this antibiotic has shown to be fatal in swine and non-human primates, and may be fatal in horses and goats. Do not use in female dairy cattle 20 months of age or older. Use in lactating dairy cattle may cause milk residues. The following adverse reactions have been reported: in cattle: injection site swelling and inflammation, lameness, collapse, anaphylaxis/anaphylactoid reactions, decreased food and water consumption, and death. Micotil has a pre-slaughter withdrawal time of 42 days.

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