Preventing BRD

On this page, you’ll find more information about how to actively prevent Bovine Respiratory Disease (BRD).

Preventative Approach

BRD is a complex and potentially fatal disease, so taking steps to prevent your cattle developing BRD is essential.

The best preventative approach is a well-managed one. Alongside an effective vaccine program, you should focus on improving the health status of your cattle and reducing environmental stress.

When it comes to preventing BRD, reducing stressors is just as important as an effective vaccination program.

Vaccination for viral and bacterial pathogens should also be implemented from a young age, so calves are exposed to BRD and can develop the appropriate antigens to prime their immune system. Elanco has a wide range of cattle vaccine options to help your herd stay healthy.The cattle vaccine portfolio is there to help you and your veterinarian maintain the health, productivity, and profitability of your operation.

Elanco’s NUPLURA® PH is the first-ever Mannheimia vaccine developed for cattle in the U.S. market using recombinant technology, which means you’re getting the purest antigen form available. NUPLURA PH has the fastest onset of immunity — The only Mannheimia (Pasteurella) haemolytica vaccine demonstrated to deliver immunity in 10 days.1

Nuplura At-A-Glance

Download our PDF to learn more about Nuplura and how it can act as a preventative BRD solution for you and your operation.


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Explore more resources to help you understand BRD and available treatment options.

Diagnosing BRD

Learn what signs to look for so you can spot BRD in your cattle.

Treating BRD

Learn about effective treatment strategies for BRD.


Micotil® (tilmicosin injection) is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus sommi, and for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica.

Important safety information

Before using this product, it is important to read the entire product insert, including the boxed human warning.Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Not for human use. Injection of this drug in humans has been associated with fatalities. Keep out of reach of children. Do not use in automatically powered syringes. Exercise extreme caution to avoid accidental self-injection. In case of human injection, consult a physician immediately and apply ice or cold pack to injection site while avoiding direct contact with skin. Avoid contact with eyes. Always use proper drug handling procedures to avoid accidental self-injection. Consult your veterinarian on the safe handling and use of all injectable products prior to administration. For use in cattle or sheep only. Inject subcutaneously. Injection of this antibiotic has shown to be fatal in swine and non-human primates, and may be fatal in horses and goats. Do not use in female dairy cattle 20 months of age or older. Use in lactating dairy cattle may cause milk residues. The following adverse reactions have been reported: in cattle: injection site swelling and inflammation, lameness, collapse, anaphylaxis/anaphylactoid reactions, decreased food and water consumption, and death. Micotil has a pre-slaughter withdrawal time of 42 days.

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